Nature Reviews Immunology is organized into the following main sections: Research Highlights, Progress, Reviews, Analysis and Perspectives.
Most of our understanding of immunological memory comes from studies in mice. However, these studies cannot recapitulate the exposure to numerous diverse pathogens that occurs over decades in humans. But, as reviewed here, recent studies focusing on human memory T cells are revealing important features of these cells, including subset heterogeneity and spatial compartmentalization.